I could imagine that being chronically deprived of quality sleep is different than skipping an entire circadian cycle once per week. Edit: I recently made the

I could imagine that being chronically deprived of quality sleep is different than skipping an entire circadian cycle once per week. Edit: I recently made the mistake (for a few months) of taking my medication before bed, rather than in the morning. This included vitamin D. Guess what happens when the body gets a dose of vitamin D at night? No quality sleep for you! So I certainly sympathize with the quest for quality sleep.