This is good news, but also shows how little we actually understand the complexity of our bodies and our brain in particular. We have good antidepressants, but

This is good news, but also shows how little we actually understand the complexity of our bodies and our brain in particular. We have good antidepressants, but besides observing the positive effects, there doesn't seem much of a consensus on what exactly these psychoactive molecules are doing to help. So no surprise that something seemly simple like sleep deprivation can have a massive effect on the issue. It's not like we understand all the mysteries of sleep either. The involved mechanism and chemistry are so complex, and we barley scrap the surface, even with all the advances in medicine. So many people arguing about what depression is, what it's causes are, but it would be foolish to assume we have this even remotely figured out, and I would be very open-minded to anything on this issue.