3 ms·
I feel like the term "epigenetics" takes on different definitions depending on context. The term can have two meanings depending which part of the term you emp
by daemonk 9y ago
I feel like the term "epigenetics" takes on different definitions depending on context.
The term can have two meanings depending which part of the term you emphasize. I think it is important to be pedantic here.
EPI-genetics with an emphasis on "epi" really describes any mechanism that happens above the genotype level. Transcription factor binding is technically "epigenetic". It is a really broad term.
Epi-GENETICS with an emphasis on "genetics" describes inheritance of information outside of the genetic information. This is probably the more interesting use of the term.
It seems like most biologist use it as a catch-all term for methylation/histone modifications/polycomb-type mechanisms. All of these mechanisms are EPI-genetic, but not all have really been proven to be epi-GENETIC.