I suspect that valproate works by increasing BDNF levels. Exercise also increases BDNF levels, and a diet high in fermentable fiber has been linked to increase

I suspect that valproate works by increasing BDNF levels. Exercise also increases BDNF levels, and a diet high in fermentable fiber has been linked to increases in BDNF as well, through increased short chain fatty acid production. It is worth mentioning that valproic acid is just a branched-chain short chain fatty acid, so it is likely that many of its effects are similar to those from short chain fatty acids derived via dietary fiber fermentation.