3 ms·

I think I've read it's for bipolar:10% if only father, 50% if both parents.

• DoreenMichele 9y ago
  And I am guessing that's not a case where they have identified specific genes. Please correct me if I am wrong. But I am not aware of bipolar genes being a thing. There is a difference between hand wavy "runs in the family, but we don't really know how it works" and a bona fide genetic disorder whose alleles have been mapped to some degree or another. Edit: To be perfectly clear, if it is not genetic and merely tends to run in families, it may be due to a variety of nongenetic factors, such as diet and lifestyle. Smoking also tends to run in families. Smoking is not a genetic disorder, though it significantly impacts health. If it is not genetic, it's heritability is not going to show up on your 23 and me profile. Fretting that it will basically means you don't know what you are talking about.
  • ddorian43 9y ago
    You are right, no genes. They are doing a study for depression + bipolar: https://www.23andme.com/depression-bipolar/ https://www.23andme.com/depression-bipolar/
    • DoreenMichele 9y ago
      There is a disease that was thought to be genetic, but was ultimately traced to ritual cannibalism spreading an infection. Relatives would eat the dead and what body part you got depended upon how closely related you were. This caused the disease to very much mimic a genetic disorder in its pattern of dispersal throughout the family. "Runs in families" needs to be very clearly distinguished from genetic disorders per se. The former suggests correlation with an as yet unidentified cause or causes, as there may be various contributing factors. The latter is a case of identified cause. Easy enough to confuse if your own life does not depend upon it, but absolutely not the same thing.