I agree. However, nothing much better is available. I loved reading work from the Santa Fe Institute and Stuart Kauffman and so on, but the reality is that desp

I agree. However, nothing much better is available. I loved reading work from the Santa Fe Institute and Stuart Kauffman and so on, but the reality is that despite their best efforts, they provided nothing better. General statements about the system-as-a-whole, but no specifics about where to look for the etiology of a specific disease or process. Nobels await those who could do more. Until such time as someone does bring theory to biology, for example, wet-labbers (not me) struggle on. I am in a little doubt as to whether general theories about complex systems could provide useful predictive frameworks, but if so, great. But until then, pre-study odds are zero if you don't do the study.