I have just such a scenario for you. Laser weapons deployed on a SpaceX BFR. The anti-missile Boeing-747 based laser weapon was cancelled by Robert Gates in 201

I have just such a scenario for you. Laser weapons deployed on a SpaceX BFR. The anti-missile Boeing-747 based laser weapon was cancelled by Robert Gates in 2012 [1] because it had limited range (about 60 miles). Put the same weapon in vacuum though, and the range extends potentially to thousands of miles. A single laser like that could potentially zap dozens of incoming ICBMs. Make these nukes fly in the lower part of the atmosphere though, and the laser won't be able to reach them. [1] https://en.wikipedia.org/wiki/Boeing_YAL-1 https://en.wikipedia.org/wiki/Boeing_YAL-1