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by Ultimatt 9y ago
You might want to sign up to be interested in our upcoming consumer product then ;D https://www.genetrainer.com/signup/ https://www.genetrainer.com/signup/
But the idea that you have absolute risk/gains from just genetics is a little unreasonable in the world of health rather than disease. For example you might have a predisposition for being incredibly stubborn and single minded (a mental trait) and utterly overcome any slightly weak cards nature dealt you for your physique. I think almost everyone can relate to that concept. We all put effort into our weaknesses most of the time, and then become highly proficient almost in what we are worst at innately! If you were told somehow your IQ is genetically average... so? IQ is a sliding scale constantly normalised as time goes on. Average IQ now is relatively much higher than a hundred years ago. The same is true with sporting achievement we have seen linear improvement in almost every sport since records started. At some point we will reach the limitation of sports science and brush up against genetic hard realities about physical muscle or oxygen transport. But not yet, and not for most people wishing to become fit and healthy. It's a genuine mix of genetics and what you are doing with your life, not some block thats genetic and then lifestyle both influence each other. You can live your life slightly abnormally to maximise your genetics. That function is very complex and personal. To talk of average risk change with genetics is almost to completely go against the whole point of the technology!
- prepend 9y agoThanks. I signed up for your beta and when check it out when I get an email seems interesting. While I agree that genes aren’t absolute, but 1) sometimes it’s pretty close and 2) it doesn’t need to be absolute if it results in improved rates of behavior change. I’m familiar with a condition with really high penetrance. So while not absolute it’s really high and almost a certainty. If computing could tell me how different risk factors or behaviors could offset or mitigate in understandable terms, that would be useful. I’ve looked at sites and they all seem to reflect pretty blah guidance that isn’t specific enough to be able to model personalized changes. But I expect that to change with all of these large genetic data sets and trials going on. Being fit and healthy would be great for everyone. But 60% of the US isn’t oversight or obese because they are stupid or lazy. It’s just hard and made harder by a very disconnected feedback loop.