3 ms·

After the replication crisis and "Why Most Published Research Findings Are False," I am very sceptical of statistical findings like this with a poorly/not under

• klmr 9y ago
  > I am very sceptical of statistical findings like this with a poorly/not understood mechanism. And you’re right to be (in fact, this is exactly the same instinct researchers get). We’ll have to wait until the actual research article is published before we can assess the quality of their evidence. But in their defence, they performed a so-called functional verification by knocking out the suspect gene (MIR206) in mice and looking for phenotypic changes. It is relatively straightforward to perform this in such a way that you get statistically robust results. And it’s also straightforward to replicate independently, which will happen in due course.