I don't have solution for everyone, but here's what I do: - take a 5 min break every ~hour and walk around office (in my country it is legal requirement that f

I don't have solution for everyone, but here's what I do: - take a 5 min break every ~hour and walk around office (in my country it is legal requirement that for every hour you spend in front of computer, you get 5 min break, so I don't have to explain that to anyone or look for excuses). - do simple exercise at desk from time to time (like standing up and down, moving head, stretching hands and back etc.) - walk to/from work (~5 km one way) whenever it's an acceptable weather outside (I use this time for thinking as I've found out that walking helps to concentrate). - exercise 3 times a week (well, at least I try to). I've never been a fan of standing desk, because due to my physical condition my back and knees start to hurt after some time standing still.