Personally, I just don't "get" the high of opiods. My experience has been entirely medical -- morphine after surgery, and the usual vicodin/percocet/whatever p

Personally, I just don't "get" the high of opiods. My experience has been entirely medical -- morphine after surgery, and the usual vicodin/percocet/whatever pills after injury or tooth extraction. Different people react to them differently. Some people, like me, they make physical pain recede, but nothing else. Some people, they make feel groggy or sick, and they don't like them. (My grandmother was like this -- she disliked the grogginess from the Brompton's Mixture more than she disliked the pain of her terminal cancer. She only took it once or twice.) And some people, one dose and it's "Where have you BEEN all my life!!!!" An interesting line of research might be -- why the difference in reaction to opiods? Why do some people get the "WOW! I LIKE that!!" reaction, while others don't?