4 ms·
Some relevant snips from that paper: > We find that the observed excess in ASD subjects of alleles positively associated with education attainment is confined
by Obi_Juan_Kenobi 9y ago
Some relevant snips from that paper:
> We find that the observed excess in ASD subjects of alleles positively associated with education attainment is confined to Asperger’s and childhood autism, and it is not seen here in atypical autism nor in other/unspecified PDD.
In simple terms: looking broadly, there appears to be meaningful genetic differences between diagnoses of childhood autism and Asperger's vs. pervasive developmental disorders (in lay terms, I'd call this 'full blown autism'). Basically, the genetic stuff that's linked to educational attainment is different from the stuff that leads to 'severe' autism.
This is especially interesting because these potentially 'good' and 'bad' traits are likely affecting the same time and location of development:
> Interestingly, both common and rare variation in ASD preferentially affects genes expressed during corticogenesis, highlighting a potential spatiotemporal convergence of genetic risk on this specific developmental epoch, despite the disorder’s profound genetic heterogeneity.
Worth noting that this is a pretty significant paper and serves as a solid foothold for the 'not a trade-off' interpretation of intelligence vs. autistic behavior. I.e., the latter is not necessarily a consequence of 'too much' of the former.