3 ms·
It goes back to basically any medication that acts on G Protein Coupled Receptors (of which opioid Receptors fall under). If given the same dose for over 10 day
by epmaybe 9y ago
It goes back to basically any medication that acts on G Protein Coupled Receptors (of which opioid Receptors fall under). If given the same dose for over 10 days, by day 3 you are seeing a significant loss of analgesic effect.