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Having close to 0 understanding on the subject can't CRISPR theoretically be used to "cut out" the virus DNA to actually cure HPV and other viruses.
by qaq 9y ago
Having close to 0 understanding on the subject can't CRISPR theoretically be used to "cut out" the virus DNA to actually cure HPV and other viruses.
- newnewpdro 9y agoI don't know how significant this [1] is a barrier to such treatments, but it seems likely to be more of a potential problem for cures vs. sensors w/potential false positives. http://newsroom.cumc.columbia.edu/blog/2017/05/30/crispr-gene-editing-can-cause-hundreds-of-unintended-mutations/ http://newsroom.cumc.columbia.edu/blog/2017/05/30/crispr-gen...
- 88e282102ae2e5b 9y agoIn theory, yes, but delivery of the CRISPR enzyme to all the infected nuclei is still an unsolved problem. Also, it doesn't cut its target every time it does get in - some of the protein is inactive (probably just broken/malformed/misfolded) - but increasing the dose to compensate leads to more instances where it cuts the wrong target.