3 ms·

Are recreational doses significantly higher than prescription doses? Why the difference?

• deleted 9y ago
  [deleted]
• jdietrich 9y ago
  Yes. "Recreational" users rarely suffer from ket bladder - it's people with serious addictions who are ending up in urology clinics. Users are reporting taking anything from 5 to 15 grams per day; even assuming that it's of very low purity, that's still orders of magnitude more than the doses being used to treat depression.
  • atomical 9y ago
    Ketamine is toxic to the bladder at any dose. I haven't found any long term research on this topic.
• DanBC 9y ago
  The research for depression used much lower doses of ketamine than recreational use. One UK clinic was using about 80 mg as a max dose. https://www.oxfordhealth.nhs.uk/news/first-uk-study-of-ketamine-for-people-with-severe-depression/ https://www.oxfordhealth.nhs.uk/news/first-uk-study-of-ketam... A large recreational dose may be 250 mg. This is partly because the recreational dose is looking for different effects, so they use more. And because people build up a tolerance.
  • IntronExon 9y ago
    It’s also a result of ketamine typically being used in the context of other drugs, especially stimulants.