5 ms·
It is in the way that alcohol use is bad for one's liver- the cases where it results in bladder issues are those of abuse where doses massively larger than the
by nylonstrung 9y ago
It is in the way that alcohol use is bad for one's liver- the cases where it results in bladder issues are those of abuse where doses massively larger than the therapeutic psychiatric dose are used on an ongoing basis.
"A young adult male taking 1 g of ketamine could expect 85% of the drug to be excreted in the urine within 24 hours, and taking into account the average voiding rate of 6 × 300 mL per day, a urine concentration in excess of 1 mmol/L is theoretically possible, suggesting the scale of in vitro toxicity reported [in the study] and by others in cancer cell lines is relevant clinically,"
For reference, the dosages this is referring to are generally .5mg/kg, which of course is comparatively small
- fragmede 9y agoBack of the envelope... 175 lb ~= 80 kg, which means a single medical dose of 40 mg, with effects lasting weeks to months, compared to abuse-levels of 1g per day!