4 ms·
It's a huge problem for recreational use. Some individuals have trouble with it even with prescription ketamine, but it's not nearly as common. Last time I aske
by blobwalker 9y ago
It's a huge problem for recreational use. Some individuals have trouble with it even with prescription ketamine, but it's not nearly as common. Last time I asked him, my doctor hasn't had any patients who were forced to discontinue treatment because of it.
n=1, but I've been receiving ketamine therapy for about 6 years and have not developed ketamine cystitis.
- collyw 9y agoAre recreational doses significantly higher than prescription doses? Why the difference?
- deleted 9y ago[deleted]
- jdietrich 9y agoYes. "Recreational" users rarely suffer from ket bladder - it's people with serious addictions who are ending up in urology clinics. Users are reporting taking anything from 5 to 15 grams per day; even assuming that it's of very low purity, that's still orders of magnitude more than the doses being used to treat depression.
- atomical 9y agoKetamine is toxic to the bladder at any dose. I haven't found any long term research on this topic.
- DanBC 9y agoThe research for depression used much lower doses of ketamine than recreational use. One UK clinic was using about 80 mg as a max dose. https://www.oxfordhealth.nhs.uk/news/first-uk-study-of-ketamine-for-people-with-severe-depression/ https://www.oxfordhealth.nhs.uk/news/first-uk-study-of-ketam... A large recreational dose may be 250 mg. This is partly because the recreational dose is looking for different effects, so they use more. And because people build up a tolerance.
- IntronExon 9y agoIt’s also a result of ketamine typically being used in the context of other drugs, especially stimulants.