4 ms·
That's to replicate the study; presumably if the authors released their trained model it would be much less computationally expensive to run it on your own data
by moyix 9y ago
That's to replicate the study; presumably if the authors released their trained model it would be much less computationally expensive to run it on your own data?
- gwern 9y agoIf by trained model you mean PGS, yes, it would be trivial. While the fitting of the optimal weights may be computationally intensive, it's still just a simple little linear model: look up the SNP value, add or subtract a small coefficient for each of the 30k or whatever 'activated' SNPs, and get the net total.