I'd add two points to the excellent comments above. My RSI was aggravated by use of the mouse. I found that using a trackpad with tap-to-click enabled helped si

I'd add two points to the excellent comments above. My RSI was aggravated by use of the mouse. I found that using a trackpad with tap-to-click enabled helped significantly. But even more important was moving all of my informational surfing, twittering, emailing, etc. to the iPad. That probably accounted for a couple hours of computer use a day. Perhaps I'll come down with "iPad wrist" in the future, but for now the different gesture patterns don't trigger the RSI pain.