20 ms·
> it's also worrying that people were prescribing medicine based on tradition rather than science Why? New drugs have been getting less effective over time, ev
by Alex3917 9y ago
> it's also worrying that people were prescribing medicine based on tradition rather than science
Why? New drugs have been getting less effective over time, even though the scientific requirements to get them approved have been becoming stricter. The majority of our most effective drugs were approved before there were any requirements for demonstrating safety and/or efficacy.
- tinokid 9y agoDoes diminishing returns/low hanging fruit mean anything to you? Also, from that pool of drugs you're referring to, we've eliminated a number of things that had strong effects but whose side-effects were later found after careful study to not outweigh the benefits. There is a similar effect from carefully studying devices/surgical interventions--not so much a raft of "new innovations" but rather the culling of a lot of things that were overused or actually harmful. Huge cost savings, big improvements in population health & lots of gored oxen.
- jostmey 9y agoDiminishing returns if we talk about small molecule drugs. But we're in the age of genetic engineering
- deleted 9y ago[deleted]