Fedora here, never had any crash. However, my laptops are Intel GPU only which hotplug just fine, and the desktop, when it had an Nvidia card had no need to be

Fedora here, never had any crash. However, my laptops are Intel GPU only which hotplug just fine, and the desktop, when it had an Nvidia card had no need to be hot plugged. Are you sure it is Gnome crashing, and not X server disappearing from under it? I also have 27" 4k. Under X11, it is not Gnome's job to do framebuffer scaling, it is display server's. Under Wayland it is, because then the Mutter compositor is the display server. So if you want macos-style framebuffer scaling under X11, use xrandr (i.e.: xrandr --display DP-2 --scale 1.15x1.15). For the above reason, the scaling coming with Gnome 3.28 is for Wayland only - and that means no Nvidia, until they sort out their API issues.