If by Microsoft you mean Exchange server, not being compatible will be a literal deal breaker in doing business. An awful lot of big players won’t host their e

If by Microsoft you mean Exchange server, not being compatible will be a literal deal breaker in doing business. An awful lot of big players won’t host their email on someone else’s service, so gmail is just not an option. If you deal with any business using primarily windows, there will also be a huge probability it’s running a Microsoft stack in full, from account management, email to file hosting.