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> Except that antibiotic resistance also goes away very quickly unless the bacteria are kept in an environment conducive to it. Antibiotic resistance is expens
by privong 9y ago
> Except that antibiotic resistance also goes away very quickly unless the bacteria are kept in an environment conducive to it. Antibiotic resistance is expensive evolutionarily.
This is the first time I've heard this. Can you recommend some references with more info on it?
- cstejerean 9y agoHere are two studies from the first page of a Google search on "losing antibiotic resistance", Long-term starvation-induced loss of antibiotic resistance in bacteria https://www.ncbi.nlm.nih.gov/pubmed/24196362 https://www.ncbi.nlm.nih.gov/pubmed/24196362 Loss of Antibiotic Resistance in Staphylococcus aureus Resulting from Growth at High Temperature http://www.microbiologyresearch.org/docserver/fulltext/micro/42/3/mic-42-3-403.pdf?expires=1518151991&id=id&accname=guest&checksum=2A3A0392A30F07ACF8F576F19F7755FA http://www.microbiologyresearch.org/docserver/fulltext/micro... And here's a more high level answer from the Biology StackExchange on the mechanism by which this happens with a link to 3 other papers on the underlying subject https://biology.stackexchange.com/a/15930 https://biology.stackexchange.com/a/15930
- saiya-jin 9y agoMy former ex-gf doing some anemia cellular research for her phd was saying exactly the same thing some 10 years ago. I understand for us laymans this is obvious and freakin' scary to think about. But in reality its not. One example I can think of - malaria & quinine. It used to be #1 go-to medication for it for a very long time, then malaria grew resistance to it, and we got malarone and whatnot so we cut usage of it. Now it's getting more effective against it again.