For your interest: https://www.ncbi.nlm.nih.gov/pubmed/12195733 https://www.ncbi.nlm.nih.gov/pubmed/12195733 Biofilms do a number of things - they can help pro

For your interest: https://www.ncbi.nlm.nih.gov/pubmed/12195733 https://www.ncbi.nlm.nih.gov/pubmed/12195733 Biofilms do a number of things - they can help promote between-organism signaling that can promote the upregulation of resistance, they can physically protect from antibiotic penetration (one of many resistance mechanisms), and they can potentially change the behavior of the bacteria itself, which will have impacts on the antibiotic's efficacy (for example, bacteriostatic antibiotics are less of a problem if bacteria aren't proliferating anyway).