Just doing some napkin math. It would be about 13,000 calls into C per frame, to waste 1 ms with call overhead. 1ms would still be a lot when you only have ~1

Just doing some napkin math. It would be about 13,000 calls into C per frame, to waste 1 ms with call overhead. 1ms would still be a lot when you only have ~16ms to work with,but I don't think even AAA games make within an order of magnitude of that many opengl calls per frame? Even writing in pure C you want to batch things as much as possible. I think typical is well under 1000 calls per frame, but I've only got experience with small hobbyist projects.