as a former scientist in immunotherapy/immunooncology research: we are going to win against cancer. and very importantly for you and your wife, many of us cons

as a former scientist in immunotherapy/immunooncology research: we are going to win against cancer. and very importantly for you and your wife, many of us consider the PD-1 therapies as the biggest battles and biggest victories that we've ever won against cancer. it is extremely difficult to overstate how powerful the anti-PD-1/L1 biologics are. and it's also extremely hard to overstate how much research scientists in the field live and breathe and toil to harness nature. you have a care staff of perhaps a dozen at the hospital, but just remember that there are tens of thousands of people working day and night to find better therapies and cures. nature is always throwing us curveballs, and in the words of rich feynman, "she's never gonna let us relax." but we'll figure it out, and win. in the meantime, that clinical trial you mentioned is investigating the true power of our biggest achievement to date. it isn't ethical to push your wife into the trial, so i'll just say this: if i had serious cancer, i'd find more than one anti-PD-1/L1 trial to try to enroll in simultaneously. that way if i got excluded from one because i didn't meet the criteria, i have a next step in hand without thinking about it any more. if by chance i got into more than one, i'd withdraw from the others (obviously). just my two cents. good luck.