I think we're already there. You can probably get around a $50 dollar bacterial genome by using robots and doing 384-well plates of samples at a time to get eco

I think we're already there. You can probably get around a $50 dollar bacterial genome by using robots and doing 384-well plates of samples at a time to get economies of scale. A lot of the costs are outside of the sequencing itself. You have to extract the DNA from the sample and prepare that DNA for the sequencing platform you're using. These costs are both the reagents needed to do this, and also the associated labour costs, even when done at scale. Perhaps you meant $100 human genome though? However I think roughly the same principles apply.