3 ms·
It's really comparing apples and oranges. If you want a 30x whole genome for genotyping, you'll use short read technologies and it'll be way less expensive. Th
by chrisamiller 9y ago
It's really comparing apples and oranges. If you want a 30x whole genome for genotyping, you'll use short read technologies and it'll be way less expensive.
The enormous reads offer a different window into genomes, by spanning repetitive regions where short reads can't be accurately placed. For lots of applications, the sweet spot is to use long reads for "scaffolding", then build up coverage with short reads.