4 ms·
There was a cool visualization from data produced on nanopore on /r/dataisbeautiful recently [1]. It really shows the strengths of the device - ~50kb region wit
by yread 9y ago
There was a cool visualization from data produced on nanopore on /r/dataisbeautiful recently [1]. It really shows the strengths of the device - ~50kb region with 3kb imperfect repeats. This would be impossible to align properly with <1kb reads from illumina. The paper is worth a read if you're interested in sequencing. They basically did a de novo sequencing of a bacterial genome on the cheap. And in the assembly they had more than 1000 reads longer than 100kb. Using this in combination with an Illumina sequencer is probably the best though.
[1]
https://www.reddit.com/r/dataisbeautiful/comments/7rpdr0/weve_published_our_nippostrongylus_brasiliensis/ https://www.reddit.com/r/dataisbeautiful/comments/7rpdr0/wev...
- comstock 9y agoThat’s great, but for a company that has raised on a valuation of >2BUSD how are they going to compete with Illumina. The read lengths might be long, but the error rate is a couple of orders of magnitude higher. I can’t see a market large enough for highly error’d log reads to support their valuation.