4 ms·

I think we will eventually realise that all degenerative brain diseases (Alzheimer's, dementia, Parkinson's, etc.) can in some way be caused by high carbohydrat

I think we will eventually realise that all degenerative brain diseases (Alzheimer's, dementia, Parkinson's, etc.) can in some way be caused by high carbohydrate (i.e. sugar - that's what it ultimately gets broken down into) intake. Byproducts of breaking down sugar in the blood stream gradually dissolve the blood-brain barrier. Depending on which part of the brain gets effected worse, results in a different neurodegenerative condition. A well referenced book on the matter: https://books.google.de/books?id=O5EODgAAQBAJ https://books.google.de/books?id=O5EODgAAQBAJ (unfortunately the name is designed for hype, but the contents are solid)

nnq 9y ago
> Byproducts of breaking down sugar in the blood stream gradually dissolve the blood-brain barrier. HUH?! Where did you get this "fact" from, I'm curious? The causal link you refer to might be true, but the "mechanism" you describe sounds antivac-class rubbish... read up some more before spreading dubious infos please.
- dang 9y ago
  This crosses into incivility. Please don't do that on HN, even when someone is wrong. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
- sleavey 9y ago
  Can we try to avoid getting personal? There is evidence suggesting diabetics are more susceptible to conditions related to elevated blood-brain barrier transport. So that might not exactly translate to "dissolving", but the effect is the same. "Changes in plasma glucose levels (hyper- or hypoglycemia) have been associated with altered BBB transport functions" [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306190/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306190/ [2] https://www.ncbi.nlm.nih.gov/pubmed/17143608 https://www.ncbi.nlm.nih.gov/pubmed/17143608
  - londt8 9y ago
    The sources look solid but you seem to mix eating carbohydrates with being diabetic. On dietary risk factors, i think sugar and bad fats are common culprits for t2 diabetes. I dont think carbs is as significant itself.

nnq 9y ago

> Byproducts of breaking down sugar in the blood stream gradually dissolve the blood-brain barrier. HUH?! Where did you get this "fact" from, I'm curious? The causal link you refer to might be true, but the "mechanism" you describe sounds antivac-class rubbish... read up some more before spreading dubious infos please.

dang 9y ago
This crosses into incivility. Please don't do that on HN, even when someone is wrong. https://news.ycombinator.com/newsguidelines.html https://news.ycombinator.com/newsguidelines.html
sleavey 9y ago
Can we try to avoid getting personal? There is evidence suggesting diabetics are more susceptible to conditions related to elevated blood-brain barrier transport. So that might not exactly translate to "dissolving", but the effect is the same. "Changes in plasma glucose levels (hyper- or hypoglycemia) have been associated with altered BBB transport functions" [1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306190/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306190/ [2] https://www.ncbi.nlm.nih.gov/pubmed/17143608 https://www.ncbi.nlm.nih.gov/pubmed/17143608
- londt8 9y ago
  The sources look solid but you seem to mix eating carbohydrates with being diabetic. On dietary risk factors, i think sugar and bad fats are common culprits for t2 diabetes. I dont think carbs is as significant itself.