5 ms·
The power is only relevant when you fail to detect an effect. This is absolutely false. Small, low-powered studies are more likely to produce false results th
by martingoodson 9y ago
The power is only relevant when you fail to detect an effect.
This is absolutely false. Small, low-powered studies are more likely to produce false results than larger studies. This was well-documented by John Ioannidis over ten years ago, in work that should be required reading for all publishing scientists:
http://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.0020124 http://journals.plos.org/plosmedicine/article?id=10.1371/jou...
- dumbneurologist 9y agoThis is addressed by pre-trial registration. You can't have publication bias (his argument) when you register the study and see that this is the only one.
- martingoodson 9y agoI know this is a dead thread: I'm answering because if you are a clinician you need to know that your understanding of the statistics is incorrect. This statistical effect has nothing to do with publication bias. If you want to continue the discussion please email me and I can explain and give copious references which will show you why.