There are cases of body integrity identity disorder (https://en.wikipedia.org/wiki/Body_integrity_identity_disorder https://en.wikipedia.org/wiki/Body_integrity

There are cases of body integrity identity disorder (https://en.wikipedia.org/wiki/Body_integrity_identity_disorder https://en.wikipedia.org/wiki/Body_integrity_identity_disord...) being treated by amputation. It's a rare condition, but the discussion about the ethics of voluntary amputation as treatment is quite extensive: https://www.ncbi.nlm.nih.gov/pubmed/15948330 https://www.ncbi.nlm.nih.gov/pubmed/15948330 https://www.ncbi.nlm.nih.gov/pubmed/19132621 https://www.ncbi.nlm.nih.gov/pubmed/19132621 https://www.ncbi.nlm.nih.gov/pubmed/17115518 https://www.ncbi.nlm.nih.gov/pubmed/17115518