The question really isn't hub-to-hub versus hub to point to point, it's hub-to-spoke versus spoke to megahub to megahub to spoke. For example, if I were going t

The question really isn't hub-to-hub versus hub to point to point, it's hub-to-spoke versus spoke to megahub to megahub to spoke. For example, if I were going to travel from Denver to Toulouse, 30 years ago my options would probably be DEN <-> JFK <-> PARIS <-> TOULOUSE. Twenty years ago, it might be DEN <-> FRA <-> TOULOUSE as the 737s and 320s displaced wide-bodies for intra-Europe flying. In ten years, as the 737-MAX, A320-NEOs, and Boeing's new Middle of the Market, you will start to see very interesting secondary markets pop up. Good case - the 787 has changed Denver so that instead of two international flights daily (To FRA and LAX) - it now has FRA, London(LHR and LGW), France, Japan, Zurich, plus every small tourist Mexican destination you can think of.