3 ms·
I notice they had to add the bacteria to the mice to do the test. I wonder if some of the instances when drugs work on mice but not in human trials are due to t
by philipodonnell 9y ago
I notice they had to add the bacteria to the mice to do the test. I wonder if some of the instances when drugs work on mice but not in human trials are due to the different gut bacteria at work?
- bastawhiz 9y agoThere are any number of reasons why drugs don't work on humans when they do work on other animals. It could be gut bacteria, but it could just be that the animal has some other physiological trait that causes the drug to be more or less effective. In this case, they weren't testing a drug, they were testing the deadliness of the bacteria. It doesn't matter _how_ toxic the bacteria is to humans relative to mice, it only matters that the bacteria is more deadly (or less deadly) to the mice when the sugar is present.