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It was definitely interesting, but it wasn't the breakthrough it was hyped-up to be. Seeing it as a 'hello world' is a cool idea, though. The hardware of the ce
by wihon 16y ago
It was definitely interesting, but it wasn't the breakthrough it was hyped-up to be. Seeing it as a 'hello world' is a cool idea, though. The hardware of the cell was ready and waiting. So Venter and his team rewrote an old program and gave it a spin. Nice.
This is more likely a lack of understanding on my part, but I'm not sure where epigenetics comes into it? The majority of the cell components - i.e. all the organelles, chemicals, etc - were already present and arranged in the 'surrogate' cell. So all the 'epigenetic' stuff was already in place. But please correct me if I'm wrong.
Not so sure about the random splicing part, either. Food manufacturers have been inserting genes into specific places on bacterial plasmids for a long a time, using directors like codon relationships and ionic interactions. Again - if I'm outta line... :)
- kragen 16y agoOh, I meant that DNA methylation (resp. phosphorylation, acetylation, etc.) wasn't preserved through the uploading / "DNA printing" process. (And I don't think the cells in question had histones.) You're right that there is potential epigenetic variation in other parts of the cell as well, but I was thinking specifically of DNA methylation. I don't actually know much about how position-specific current transgenic techniques are, so I could be wrong about that.