Great reference, thanks! From the link you provided: According to the report, the transition from an initial prescription to chronic use begins very early on.

Great reference, thanks! From the link you provided: According to the report, the transition from an initial prescription to chronic use begins very early on. Even a one-day opioid prescription carried a 6 percent risk of use at one year later and a 2.9 percent risk of use at three years later. The sharpest increases in the likelihood of long-term use came at five days after the initial prescription, with another spike seen at one month. Whoa! That's frightening.