It depends on how extreme your standard for break with reality is. Most trip reports I've read indicate a break with consensus interpretation of reality, which

It depends on how extreme your standard for break with reality is. Most trip reports I've read indicate a break with consensus interpretation of reality, which is consistent with psychosis. I have experienced bipolar psychosis twice, and LSD psychosis ~12 times, and subjectively they are far more similar than not. I'd say they are only barely distinguishable by subtle intangibles. Again, subjectively.