I have at different points in my life had major depressive episodes where an ssri does nothing whatsoever, and others when the same ssri same dose completely kn

I have at different points in my life had major depressive episodes where an ssri does nothing whatsoever, and others when the same ssri same dose completely knocked it out. I’ve never seen a single study that shows altnernative efficacies in the same person, but it happened to me. Just one data point though.