4 ms·

Actually no. SSRIs, and their more recent variants, would almost invariably comprise that first and second courses of treatments.

• tpm 9y ago
  Which is exactly what I'm talking about, against your original claim that "SSRIs are used to treat a different class of depression" sorry if this wasn't clear enough from my post, English is not my first language.
  • WalterSear 9y ago
    Except still not. It's not treatment resistant depression until the other stuff hasn't worked. Treatment resistant depression isn't a more exact diagnosis: it's an admission that the previous diagnosis was wrong, and the disease is a different one, with a different etiology and a different form of treatment - both pharmaceutical and from the standpoint of therapy.
    • tpm 9y ago
      Yes, and the other stuff that didn't work is most of the time SSRI. Treatment resistant depression is not a class of depression like bipolar or psychotic. It can be any depression that resisted the given treatment - that does not mean that the previous diagnosis was wrong. Exactly like when you diagnose a particular cancer and the the treatment does not work. It's still the same cancer. It has not morphed into something else, it has not jumped to a different type of cell. It just means your treatment options are limited and in this case they didn't work.