3 ms·

How about banning BS psychology HN comments, too? It sounds like you're basically talking about ego depletion, which has come under fire in the past few years,

How about banning BS psychology HN comments, too? It sounds like you're basically talking about ego depletion, which has come under fire in the past few years, with what little evidence there was for it coming into doubt: https://en.wikipedia.org/wiki/Ego_depletion https://en.wikipedia.org/wiki/Ego_depletion

fragmede 9y ago
How about banning BS-BS psychology HN comments, too? It sounds like you don't believe ADHD is a real disease, which has come under fire in the past few years due to skyrocketing rates of diagnosis, with pop psychologists believing that it's a scam by the pharmaceutical industry. https://en.wikipedia.org/wiki/Attention_deficit_hyperactivity_disorder https://en.wikipedia.org/wiki/Attention_deficit_hyperactivit...
- Sir_Cmpwn 9y ago
  Jesus christ, I never said I don't believe in ADHD. Don't put words like that in my mouth.
iandanforth 9y ago
I respect the spirit of your response but no. Here are some interesting studies. One of many candidate drug evaluations - https://academic.oup.com/ijnp/article/17/12/2045/2910067 https://academic.oup.com/ijnp/article/17/12/2045/2910067 Dosage dependant effects and tolerance - https://www.ncbi.nlm.nih.gov/m/pubmed/2530095/ https://www.ncbi.nlm.nih.gov/m/pubmed/2530095/ Environment protecting against addiction - https://www.ncbi.nlm.nih.gov/m/pubmed/22157144/ https://www.ncbi.nlm.nih.gov/m/pubmed/22157144/ Edit - Couldn't find a good source for the bear thing. Apologies!
- PragmaticPulp 9y ago
  Reductionist arguments based on narrowly-scoped rodent studies are not appropriate in the context of long-term human motivation. "Motivation is a chemical state" is a tautology in the context of psychology. Every human behavior and emotion derives from the chemical state of the brain. If someone is chronically unsatisfied with their life, would you reduce their concerns to "Happiness is a chemical state"? Stating as much does not add value to the discussion, nor is it actionable. Likewise, in the context of human motivation it's not relevant to discuss rodent lever-pushing behavior following acute administration of large doses of high-potency DAT inhibitors. If someone is unhappy, would you provide links to studies showing that rodent display increased liking behaviors after administration of a potent opioid? Stimulants like Adderall do induce generic motivation in the short-term, but that's not anyone is discussing here. Implying that stimulants are a source of motivation is dangerous advice. The motivational effects are largely temporary, and quickly give way to tolerance. Note that the attention-improving effects mostly remain in this case. Drug abusers who seek motivation-boosting effects from stimulants either give up after tolerance sets in, or they settle into patterns of dose escalation in a futile attempt to outrun tolerance. Dopaminergic stimulant abusers often have extremely high motivation during their binges, but it does not translate to anything useful after marathon obsessive cleaning sessions or internet binges. That's because motivation, in the context of what we're discussing here, is far more complex than just modulating your brain's dopaminergic systems with chemicals. Motivation is a much broader topic that involves discipline, goal-oriented behavior, prioritization, self-reflection, and many other complex phenomena that can't be reduced into a singular brain chemical like dopamine.
sizzle 9y ago
His response is sound neuroscience.
kortex 9y ago
Irrespective of ego depletion hypothesis, dopamine is still one of the primary modulators of motivation, risk, decision, and impulse. Absolute levels of dopamine, ratios of various subtypes (D1 vs D2 vs ...), and differential activation, in the NA, VTA, and substantia nigra affect everything from the ADHD kid wiggling in his seat, to the gambling addict. Unfortunately, things like dopaminergic drugs are a blunt instrument, and it's not as simple as "add adderall, get productivity". The role of dopamine in risk taking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038955/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038955/ Dopaminergic Modulation of Risk-Based Decision Making https://www.nature.com/articles/npp2008121 https://www.nature.com/articles/npp2008121 Procrastination and Dopamine Receptor Density https://www.psychologytoday.com/blog/intrinsic-motivation-and-magical-unicorns/201206/procrastination-and-dopamine-receptor-density https://www.psychologytoday.com/blog/intrinsic-motivation-an...

fragmede 9y ago

How about banning BS-BS psychology HN comments, too? It sounds like you don't believe ADHD is a real disease, which has come under fire in the past few years due to skyrocketing rates of diagnosis, with pop psychologists believing that it's a scam by the pharmaceutical industry. https://en.wikipedia.org/wiki/Attention_deficit_hyperactivity_disorder https://en.wikipedia.org/wiki/Attention_deficit_hyperactivit...

Sir_Cmpwn 9y ago
Jesus christ, I never said I don't believe in ADHD. Don't put words like that in my mouth.

iandanforth 9y ago

I respect the spirit of your response but no. Here are some interesting studies. One of many candidate drug evaluations - https://academic.oup.com/ijnp/article/17/12/2045/2910067 https://academic.oup.com/ijnp/article/17/12/2045/2910067 Dosage dependant effects and tolerance - https://www.ncbi.nlm.nih.gov/m/pubmed/2530095/ https://www.ncbi.nlm.nih.gov/m/pubmed/2530095/ Environment protecting against addiction - https://www.ncbi.nlm.nih.gov/m/pubmed/22157144/ https://www.ncbi.nlm.nih.gov/m/pubmed/22157144/ Edit - Couldn't find a good source for the bear thing. Apologies!

PragmaticPulp 9y ago
Reductionist arguments based on narrowly-scoped rodent studies are not appropriate in the context of long-term human motivation. "Motivation is a chemical state" is a tautology in the context of psychology. Every human behavior and emotion derives from the chemical state of the brain. If someone is chronically unsatisfied with their life, would you reduce their concerns to "Happiness is a chemical state"? Stating as much does not add value to the discussion, nor is it actionable. Likewise, in the context of human motivation it's not relevant to discuss rodent lever-pushing behavior following acute administration of large doses of high-potency DAT inhibitors. If someone is unhappy, would you provide links to studies showing that rodent display increased liking behaviors after administration of a potent opioid? Stimulants like Adderall do induce generic motivation in the short-term, but that's not anyone is discussing here. Implying that stimulants are a source of motivation is dangerous advice. The motivational effects are largely temporary, and quickly give way to tolerance. Note that the attention-improving effects mostly remain in this case. Drug abusers who seek motivation-boosting effects from stimulants either give up after tolerance sets in, or they settle into patterns of dose escalation in a futile attempt to outrun tolerance. Dopaminergic stimulant abusers often have extremely high motivation during their binges, but it does not translate to anything useful after marathon obsessive cleaning sessions or internet binges. That's because motivation, in the context of what we're discussing here, is far more complex than just modulating your brain's dopaminergic systems with chemicals. Motivation is a much broader topic that involves discipline, goal-oriented behavior, prioritization, self-reflection, and many other complex phenomena that can't be reduced into a singular brain chemical like dopamine.

sizzle 9y ago

His response is sound neuroscience.

kortex 9y ago

Irrespective of ego depletion hypothesis, dopamine is still one of the primary modulators of motivation, risk, decision, and impulse. Absolute levels of dopamine, ratios of various subtypes (D1 vs D2 vs ...), and differential activation, in the NA, VTA, and substantia nigra affect everything from the ADHD kid wiggling in his seat, to the gambling addict. Unfortunately, things like dopaminergic drugs are a blunt instrument, and it's not as simple as "add adderall, get productivity". The role of dopamine in risk taking https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038955/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4038955/ Dopaminergic Modulation of Risk-Based Decision Making https://www.nature.com/articles/npp2008121 https://www.nature.com/articles/npp2008121 Procrastination and Dopamine Receptor Density https://www.psychologytoday.com/blog/intrinsic-motivation-and-magical-unicorns/201206/procrastination-and-dopamine-receptor-density https://www.psychologytoday.com/blog/intrinsic-motivation-an...