5 ms·

I noticed no effect from microdosing mushrooms (0.5g per day for a few days) but I don't suffer from depression. How long did microdosing take to make a meaning

• heavenlyblue 9y ago
  I have noticed being more emotional in general (ups and higher, downs are lower). But in my case I would be dosing 0.5g several times a day over the course of three days; knowing that the effect keeps for around 3 hours at +1H. On the other hand at that point of time I did suffer from depression and they would kick me out of the relatively low-peak baseline. I have repeated this a few times.
  • blobwalker 9y ago
    A low baseline is common in bipolar disorder, too. It was (and to a lesser but unfortunate degree, still is) very commonly misdiagnosed as depression because of this. It reacts quite differently to drugs than depression; many anti-depressants pose a high suicide risk when taken by bipolar individuals. While the overall effect during depressive periods (which can last years) in bipolar seems the same, it seems to have a different underlying cause. Normally you wouldn’t get cycling that fast, but AFAIK, there is even less research so far about how psilocybin affects bipolar disorder. I’m not trying to diagnose anyone... just something to think about for anyone who thinks they might be suffering from depression. I think I was misdiagnosed for many years, leading to decades of ineffective treatments.
• heavenlyblue 9y ago
  By the way, certain combinations tend to highlight the fact that you have indeed dosed and it’s not placebo: try making a coffee with the same 0.5g dosage and you’d see that the stimulating effect of the coffee is way more expressed at +1H.
• ttul 9y ago
  This is very poorly understood.