Anecdotally, one-time use of LSD(which acts similarly to psilocybin, primarily through 5-ht2a agonism) set me on a path to self improvement. I had depression fo

Anecdotally, one-time use of LSD(which acts similarly to psilocybin, primarily through 5-ht2a agonism) set me on a path to self improvement. I had depression for years during my puberty, teens, and early adulthood. I contemplated suicide regularly and had a pessimistic outlook on life. I dropped out of college in my first semester despite taking and passing multiple AP classes in high school because I didn't see the point of college. Then I took a large dose of LSD once. It was a very unpleasant experience. The changes weren't immediate, but in the following months, my outlook started to change. I started caring about life again, quit smoking and started exercising, and went back to college. Now, I'm completely drug free, have a wife and a degree, and am optimistic for the future. I wouldn't recommend other people try it, because my experience made me understand why some people go insane from it. I believe, though, that it put me on a path of self-improvement, and should absolutely continue to be studied.