The primary missions in drug development are efficacy and safety. AI can help answer clear well-formed efficacy questions like, "Does this molecule fit a chose

The primary missions in drug development are efficacy and safety. AI can help answer clear well-formed efficacy questions like, "Does this molecule fit a chosen target molecule"? But it can't help with bigger efficacies like, "Will hitting this target make a sufficient difference in managing this disease"? Or any safety questions like, "Does the molecule also hit any other molecules somewhere in the body (or population) that might screw up something else"? And unfortunately it's safety failures that eat up 90% of drug development costs (esp. in Phase III). Until Wall St (or Sand Hill Rd) understands that domain-agnostic low-info approaches like AI are incapable of answering complex questions that require teams of PhDs steeped in decades of doing both chemistry and biology, the notion of CADD will continue to miss the mark and waste megabucks.