3 ms·

https://media.jamanetwork.com/news-item/no-significant-difference-pain-relief-opioids-vs-non-opioid-analgesics-treating-arm-leg-pain/ https://media.jamanetwork.

• Nursie 9y ago
  While that is interesting (and a little surprising), it's one measure on one sort of pain. It doesn't look at speed of onset, length of effect or the health impact of repeated dosing - paracetamol is not all that well tolerated by the body and ibuprofen can irritate the stomach. I'm also surprised because I'm sure I read sometime last year that for some types of pain, paracetamol is indistinguishable from placebo.
  • rabidrat 9y ago
    Note that this is very specifically ibuprofen AND paracetamol taken together. You're right that both of these drugs can be hard on various internal organs. But compared to opiates? From the opioid epidemic to my personal experience, there is no comparison as to which has larger consequences.