You can make an immune response to anything by attaching it to a larger molecule that is immunogenic. There are already vaccine to morphine induced by immunisat

You can make an immune response to anything by attaching it to a larger molecule that is immunogenic. There are already vaccine to morphine induced by immunisation [1]. Of course all the vaccines developed to date have been aimed at blocking the morphine reaching the brain (an approach that won’t work), but there is nothing to stop someone developing a vaccine that induces anaphylaxis instead (other than ethics). 1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773503/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773503/