I don’t know any research but I can speak for my own experience. I am not a runner and wear them almost exclusively for 4 months. I’m relatively fit and work a

I don’t know any research but I can speak for my own experience. I am not a runner and wear them almost exclusively for 4 months. I’m relatively fit and work at a standing desk (mostly standing sometimes sitting). I have small miniscus tears in my knees. When I exercise regularly (bike or elliptical 2x per week) my knees don’t bother me. I also had some pain the balls of my feet. For the past few months I have not had the chance to exercise regularly. After switching to minimalist “barefoot” shoes, the pain the balls of my feet are gone and even without the regular excercise my knees feel pretty good. I’ve even felt good after working our booth at 3 long tradeshows this past fall. I don’t think I’m one to fall for fads. I’m converted to this style shoe now. Ymmv