This is a Mayo Clinic commentary on a publication in Neurology: http://n.neurology.org/content/early/2017/12/27/WNL.0000000000004826 http://n.neurology.org/cont

This is a Mayo Clinic commentary on a publication in Neurology: http://n.neurology.org/content/early/2017/12/27/WNL.0000000000004826 http://n.neurology.org/content/early/2017/12/27/WNL.00000000... in which a group of physicians "systematically reviewed MCI prevalence, prognosis, and treatment." The recommendations specifically apply to Mild Cognitive Impairment, which is a pre-Alzheimer's like condition where cognitive function has declined significantly from age-norms or recent history, but not enough to interfere with activities of daily living (and so does not meet the diagnostic criteria for Alzheimer's/dementia). What's interesting about the review is that for the first time, two interventions are suggested: physical exercise (as mentioned in the headline), and cognitive training. Pharmaceuticals for Alzheimer's are commonly prescribed for MCI; but this review specifically notes that no high quality evidence exists for their efficacy in MCI.