I personally think the combination of the (legal, or at least government approved) prescription opioid crisis, combined with the relatively successful decrimina

I personally think the combination of the (legal, or at least government approved) prescription opioid crisis, combined with the relatively successful decriminalization at various levels of cannabis in several states, has really changed the tone of conversation on pharmaceutical compounds, recreational or otherwise. Old paradigms (particularly ones that are not 100% based on factual / scientific analysis, as drug law tended to be) die hard, and it will take some time to change laws as a result. But the moral panic over "illegal drugs" is way less these days than it was in, say, the 1980s.