Absolutely. It's really not that hard. I did it with the first version of my little meeting agenda app Meeting Rainbow. I rewrote the UI using Angular 1.4 later

Absolutely. It's really not that hard. I did it with the first version of my little meeting agenda app Meeting Rainbow. I rewrote the UI using Angular 1.4 later, and honestly it wasn't any easier using Angular than no framework. Angular just made things different, and depending on your opinion made the code easier to understand (though both versions are several years old at this point and far from what I'd consider a good codebase.)