Not really, I mean, your opponent is the one controlling the size of the thing you're trying to intercept and they're not going to be trying to make things easi

Not really, I mean, your opponent is the one controlling the size of the thing you're trying to intercept and they're not going to be trying to make things easier on you. The only viable option given that is to go for area saturation and basically play the odds, but that's really expensive because not only do you need lots of interceptors in that case, but each one needs to be capable of getting a kinetic kill since there's no guarantee which one (if any) will actually hit. At some point I imagine the interceptors become a bigger danger to each other than they are to the thing you're trying to intercept.